Effects of ursolic acid on sub-lesional muscle pathology in a contusion model of spinal cord injury
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چکیده
منابع مشابه
A contusion model of severe spinal cord injury in rats.
The translational potential of novel treatments should be investigated in severe spinal cord injury (SCI) contusion models. A detailed methodology is described to obtain a consistent model of severe SCI. Use of a stereotactic frame and computer controlled impactor allows for creation of reproducible injury. Hypothermia and urinary tract infection pose significant challenges in the post-operativ...
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αB-crystallin is a member of the heat shock protein family that exerts cell protection under several stress-related conditions. Recent studies have revealed that αB-crystallin plays a beneficial role in a mouse model of multiple sclerosis, brain ischemia, and Alexander disease. Whether αB-crystallin plays a role in modulating the secondary damage after CNS trauma is not known. We report here th...
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Background: Chondroitinase ABC (cABC), due to its loosening impact on the extracellular matrix scaffold, has been used to enhance regeneration of injured axonal tracts after spinal cord injury (SCI). However, cABC thermal instability at physiological temperature has limited its clinical application. The disaccharide trehalose has been shown to increase the stability of cABC in body temperature....
متن کاملeffect of sub-grid scales on large eddy simulation of particle deposition in a turbulent channel flow
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15 صفحه اولenhanced neuropathic pain following intraspinaly injection of schwann cells in contusion model of spinal cord injury
enhanced neuropathic pain following intraspinaly injection of schwann cells in contusion model of spinal cord injury pourheydar b [1] *, joghataei mt [2] , najafzadeh n [3] received: 6 nov , 2011 accepted: 20 jan , 2012 abstract background & aims : spinal cord injury (sci) leads to sensorimotor deficits and neuropathic pain (np). cell therapy is a common method for treatment of sc...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0203042